Clinical Likelihood And Rule Interpretation Tool (for You)
For clinician use only Not a substitute for clinical judgement
Select a CPR study
Choose a validated clinical prediction rule from the library, then select which test or cluster to analyse.
Select test or cluster
Select a study and test above to populate the calculator.
Pre-test probability
Adjust to reflect your clinic's case mix. Study prevalence is shown as a reference point — your setting may differ significantly.
32%
Contingency table
Condition present
Condition absent
Total
Test +
—
—
—
Test −
—
—
—
Total
—
—
—
Diagnostic accuracy
Sensitivity
—
TP/(TP+FN)
Specificity
—
TN/(TN+FP)
PPV
—
TP/(TP+FP)
NPV
—
TN/(TN+FN)
LR+ (positive likelihood ratio)
—
How much more likely a positive result in someone WITH the condition. Target >10 for strong rule-in.
Sn / (1−Sp)
LR− (negative likelihood ratio)
—
How much more likely a negative result in someone WITHOUT the condition. Target <0.1 for strong rule-out.
(1−Sn) / Sp
Post-test probability
If test positive
—
Pre-test odds × LR+
If test negative
—
Pre-test odds × LR−
Manual entry
Enter raw cell counts from any diagnostic accuracy study. All statistics calculate automatically.
TP Disease+, Test+
FP No disease, Test+
FN Disease+, Test−
TN No disease, Test−
Pre-test probability
30%
Contingency table
Condition present
Condition absent
Total
Test +
—
—
—
Test −
—
—
—
Total
—
—
—
Diagnostic accuracy
Sensitivity
—
TP/(TP+FN)
Specificity
—
TN/(TN+FP)
PPV
—
TP/(TP+FP)
NPV
—
TN/(TN+FN)
LR+
—
Target >10 for strong rule-in.
Sn / (1−Sp)
LR−
—
Target <0.1 for strong rule-out.
(1−Sn) / Sp
Post-test probability
If test positive
—
Pre-test odds × LR+
If test negative
—
Pre-test odds × LR−
Import a new CPR study
Fill in the study details and add each test or cluster with its raw 2×2 cell counts. The study will be saved to the shared library and available to all CLARITY users immediately.